"In the meantime the morphine had its customary effect- that of enduing all the external world with an intensity of interest. In the quivering of a leaf- in the hue of a blade of grass- in the shape of a trefoil- in the humming of a bee- in the gleaming of a dew-drop- in the breathing of the wind- in the faint odors that came from the forest- there came a whole universe of suggestion- a gay and motley train of rhapsodical and immethodical thought."
Poe didn't use drugs to "get high" -- he used drugs to truly appreciate the world around him. Freud didn't use cocaine to get high -- he used it to goad himself on to become prolific. Thomas De Quincey used opium to better enjoy the opera and Benjamin Franklin did so just because he wanted to -- but that was back at a time when people still judged other people for how they actually behaved, as opposed to what substances they happened to have ingested.