How depressed Americans blame themselves for the problems caused by drug prohibition
by Brian Ballard Quass, the Drug War Philosopher
November 25, 2025
It is becoming increasingly difficult for me to separate my philosophical life from my casual life with friends. That is because, unbeknownst to themselves, the latter keep saying and doing things that tragically illustrate the problems with drug prohibition. I am thinking especially of the increasing number of my friends who are "coming out" as being depressed. They always do so in a predictable fashion, by making a somewhat lengthy tell-all speech, either in person or by mail, in which they confess to having been depressed for a long time now and to having even contemplated suicide, reporting however that they have finally seen the light. They now see that they are sick and that they need help. They speak of their determination to join a variety of self-help groups and report that they have already visited a psychiatrist, from whom they have received an antidepressant which they trust will help them correct their recalcitrant biochemistry and so make them comfortable once again in their own skin. They thank us for our time and our understanding and invite our advice and suggestions on upbeat protocols moving forward. They then sit back, as it were, in expectation of the compassion and reassurance that such an intimate confession must necessarily elicit from all but the most callous of hearts.
Such avowals place me in a very awkward position. Should I attempt to give this naive sufferer "the big picture" regarding his or her situation -- should I tell them how cocaine is a godsend for depression1 and how medical doctors helped outlaw the drug for obvious self-interested reasons2 -- or should I just make with the expected back-patting while perhaps adding a few reciprocal confessions of my own in order to break the ice, which might be imagined to be quite thick after such confessions, especially if both confessor and penitent are of the masculine sex. Even if I decide to be honest, it is not clear what advice I should give in the age of the Drug War. Should I be troubled by the idea that my friend has committed to the use of a drug that will likely turn him or her into a patient for life? or should I let that decision go unchallenged in recognition of the fact that Big Pharma drugs, however problematic and inadequate they may be, are the only game in town when it comes to pharmacological relief in the age of drug prohibition? That latter decision, of course, will probably depend on how close the world may be to drug relegalization at the time, at least somewhere on the globe. If any country were likely to re-legalize drug use on principle in the near future, and so re-legalize our right to take care of our own health, then I would counsel my depressed friend to seriously consider relocating to that enlightened country when such a change came about, in the meantime foregoing the use of "meds" which may prove to be "un-kickable" in the long run3.
I do not mean to scoff at these heartfelt avowals, only to point out that these misguided penitents are essentially apologizing for a crime that they never committed. It is drug prohibition which brought about their depression by outlawing endless godsends, many of which could have treated the blues in real-time and helped them take both depression and themselves less seriously. Cocaine could have cured their depression in a trice, as Sigmund Freud knew from personal experience4. But there are many other drugs that could have helped as well. Consider the following reports from users of the phenethylamines synthesized by American chemist Alexander Shulgin56:
"The feeling was one of great camaraderie, and it was very easy to talk to people."
"Excellent feelings, tremendous opening of insight and understanding, a real awakening."
"I acknowledged a rapture in the very act of breathing."
Why then are so many Americans depressed? It is because Puritans of our time are more ambitious than their forebears. The Puritans of yore insisted merely that their homes and places of worship be simple and unadorned. The Puritans of today insist that the soul of humankind be just as simple and unadorned, hence the War on Drugs to outlaw all substances whose use might inspire or facilitate any new and therefore frightening ways of being in the world.
It will be objected that some people are "really" depressed, thanks to their biochemistry, for instance. But we cannot know if that is true -- or if that even MATTERS -- until we purposefully attempt to leverage the vast array of psychoactive medicines to end depression in a vast variety of specific cases. Before we can do this, however, we need to create a new field of professionals, which I call pharmacologically savvy empaths7, who, unlike modern materialist doctors, would take common-sense psychology into account in advising on wise drug use. Unlike materialist doctors, these empaths would see at once that laughing gas and cocaine have glaringly obvious uses for the depressed and that the protocols for their wise and beneficial use are limited only by the human imagination. Unlike materialist doctors, these empaths would understand the value of anticipation8, the value of virtuous circles, and the value of turning success into a habit with the strategic use of psychoactive medicines. Unlike materialist doctors, these empaths would understand that it is absurd to promote brain-damaging shock therapy while yet outlawing the kinds of drugs that would render such "therapy" unnecessary9. We need, in other words, to finally realize in the western world that it was a category error to place materialists in charge of mind and mood medicine in the first place.
CHRISTIANITY IS DEAD! LONG LIVE CHRISTIANITY!
One cannot help but notice a religious aspect to the sort of confessions mentioned above. This puts one in mind of Nietzsche's claim that Christian values continue to regulate behavior in the west even though Christianity as a religion would seem to be in decline10. One can no longer come home to the Church, perhaps, having long-since replaced one's faith with a naive belief in the omnipotence of science, but one still feels a psychospiritual need to come home -- to play the prodigal and to be welcomed back once again into the fold. Perhaps this helps explain why so few depressives connect the dots between their condition and drug prohibition. Although they are no longer practicing Christians, they embrace the assumptions about morality that were championed by the Christian Nationalists who started the original War on Drugs in the latter 19th and early 20th centuries11, including the idea that drug use is sin. From this it follows that only "meds" can be used to treat depression and that therefore no conspiracy exists when it comes to drugs and depression. Of course, Americans consider it to be scientifically incorrect to speak of sin these days. They therefore secularize and psychologize their problems. But they do so in such a way as to give themselves the cathartic benefits of Christianity in the form of redemption, albeit a redemption that is achieved on humanistic rather than religious grounds.
Author's Follow-up:
November 26, 2025
My main point, I hope, is an implicit corollary to what I have written above: namely, that the depressed should be spending their free time protesting drug prohibition with their fellow depressed, rather than engaging with them in maudlin exchanges about the challenges that they face in life -- or about the relative merits of one dependence-causing Big Pharma "med" over another. They should leverage the power of a just indignation to stand up for their rights to heal rather than pretending that their life situation came about naturally, as it were, by an unlucky throw of the dice. No, they are depressed because of drug prohibition, and until they recognize that fact and begin to push back in the name of healthcare freedom, their suffering will be in vain.
The Drug War shows us that American democracy is fundamentally flawed. Propaganda and fearmongering has persuaded Americans to give up freedoms that are clearly enunciated in the U.S. Constitution. We need a new democracy in which a Constitution actually matters.
And where did politicians get the idea that irresponsible white American young people are the only stakeholders when it comes to the question of re-legalizing drugs??? There are hundreds of millions of other stakeholders: philosophers, pain patients, the depressed.
When we place the FDA in charge of deciding whether a psychoactive drug should be re-legalized or not, we are asking them to decide on things like the relative importance of appreciating a sunset, a task for which the FDA has no expertise whatsoever.
People say shrooms should not be used by those with a history of "mental illness." But that's one of the greatest potential benefits of shrooms! (They cured Stamets' teenage stuttering.) Some folks place safety first, but if I did that, I'd die long before using mother nature.
Being less than a month away from an election that, in my view, could end American democracy, I don't like to credit Musk for much. But I absolutely love it every time he does or says something that pushes back against the drug-war narrative.
Drug War censorship is supported by our "science" magazines, which pretend that outlawed drugs do not exist, and so write what amount to lies about the supposed intransigence of things like depression and anxiety.
All drugs have positive uses at some dose, for some reason, at some time -- but prohibitionists have the absurd idea that drugs can be voted up or down. This anti-scientific notion deprives the modern world of countless godsends.
All uplifting drugs are potential antidepressants. Science denies that fact by claiming that drug efficacy must be proven quantitatively. And so they ignore anecdote, history and psychological common sense.
The book "Plants of the Gods" is full of plants and fungi that could help addicts and alcoholics, sometimes in the plant's existing form, sometimes in combinations, sometimes via extracting alkaloids, etc. But drug warriors need addiction to sell their prohibition ideology.
At best, antidepressants make depression bearable. We need not settle for such drugs, especially when they are notorious for causing dependence. There are many drugs that elate and inspire. It is both cruel and criminal to outlaw them.
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