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The addiction gene should be called the prohibition gene: it renders one vulnerable to prohibition lies and limitations: like the lack of safe supply, the lack of choices, and the lack of information. We should pathologize the prohibitionists, not their victims.
Psychedelics and entheogens should be freely available to all dementia patients. These medicines can increase neuronal plasticity and even grow new neurons. Besides, they can inspire and elate -- or do we puritans feel that our loved ones have no right to peace of mind?
Americans HATE big government -- and yet they have no problem with government using drug prohibition to control their pain relief and how and how much they can think and feel in this life.
Philip Jenkins reports that Rophynol had positive uses for treating mental disorders until the media called it the "date rape drug." We thus punished those who were benefitting from the drug, tho' the biggest drug culprit in date rape is alcohol. Oprah spread the fear virally.
Many psychonauts (like Terence McKenna) praise psychedelics while demonizing other psychoactive substances. No substance is bad in itself. All substances have some use at some dose for some reason for some people in some circumstance.
You can get a Ph.D. in healthcare, and not learn a thing about the glaringly obvious benefits of drugs, as demonstrated by history, anecdote and common sense.
Imagine if we held sports to the same safety standard as drugs. There would be no sports at all. And yet even free climbing is legal. Why? Because with sports, we recognize the benefits and not just the downsides.
That's another problem with "following the science." Science downplays personal testimony as subjective. But psychoactive experiences are all ABOUT subjectivity. With such drugs, users are not widgets susceptible to the one-size-fits-all pills of reductionism.
As such, "we" are important. The sun is just a chaos of particles that "we" have selected out of the rest of the raw data and declared "This we shall call the sun!" "We" make this universe. Consciousness is fundamental.
If there were no other problem with antidepressants, they would be wrong for the simple reason that they make a user dependent for life -- not as a bug (as in drugs like opium) but rather as a feature: that's how they "work," by being administered daily for a lifetime.

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