It's a category error to say that scientists can tell us if psychoactive drugs "really work." It's like asking Dr. Spock of Star Trek if hugging "really works." ("Hugging is highly illogical, Captain.")
I, for one, am actually TRYING to recommend drugs like MDMA and psilocybin as substitutes for shock therapy. In fact, I would recommend almost ANY pick-me-up drug as an alternative to knowingly damaging the human brain. That's more than the hateful DEA can say.
"When two men who have been in an aggressive mood toward each other take part in the ritual, one is able to say to the other, 'Come, let us drink, for there is something between us.' " re: the Mayan use of the balche drink in Encyc of Psych Plants, by Ratsch & Hofmann
Here's the first step in the FDA process for evaluating a psychoactive drug:
Ignore all glaringly obvious benefits
Just saw a prosecutor gloating about the drug dealers she has taken down. What a joke. How much is she getting paid to play whack-a-mole? RE-LEGALIZE MIND AND MOOD MEDICINE!
This hysterical reaction to rare negative events actually creates more rare negative events. This is why the DEA publicizes "drug problems," because by making them well known, they make the problems more prevalent and can thereby justify their huge budget.
"Can I use poppies, coca, laughing gas, MDMA?" "NO," says the materialist, "We must be SCIENTIFIC! We must fry your brain and give you a lobotomy and make you a patient for life with the psychiatric pill mill! That's true SCIENCE!"
Getting off antidepressants can make things worse for only one reason: because we have outlawed all the drugs that could help with the transition. Right now, getting off any drug basically means becoming a drug-free Christian Scientist. No wonder withdrawal is hard.
Oregon has decided to go back to the braindead plan of treating substance use as a police matter. Might as well arrest people at home since America has already spread their drug-hating Christian Science religion all over the world.
I hope that scientists will eventually find the prohibition gene so that we can eradicate this superstitious way of thinking from humankind. "Ug! Drugs bad! Drugs not good for anyone, anywhere, at any dose, for any reason, ever! Ug!"