PS I'm one of psychiatry's millions of "eternal patients" in these days of the addictive pill paradigm, and so I have 40+ years of experience on the receiving end of psychiatric nostrums for fighting depression and anxiety. Given this vast experience, I hope you'll consider it worthwhile to read a criticism that I have of the scientific method when it comes to seeking out and justifying cures for depression.
The reductionist approach is always looking for "mechanisms of action," but it is my belief that this focus blinds researchers to common sense in many cases. Take MDMA , for instance. Given my secondhand knowledge of the effects of MDMA (as described both by "ravers" and by your study participants), I have sufficient information to know that MDMA would be an effective psychotherapeutic adjunct when used, say, between once a week and once a month in a psychiatrist's office. My conclusion, however, is based on a knowledge of human nature to which reductionist science gives little attention: the fact that a human being looks forward to positive experiences, and that this very anticipation can improve the quality of one's mental life.
If I were to propose such therapy, the reductionist might instinctively object: "But we want to know the mechanism of action before we proceed: namely, how does MDMA decrease depression in this case: what are the chemical mechanisms involved?" This statement, however, merely indicates that the scientist "just doesn't get it." The scientist wants to go in search of a phantom. The MDMA does not have to decrease depression directly in order to decrease depression. Its use simply constitutes an extremely positive experience, and anticipation of use does the rest of the work in decreasing the user's overall depression.
This is why drugs like cocaine and opium can be successfully vilified by Drug Warriors: they can (perhaps correctly) say that there is no direct chemical link between use and self-fulfillment or happiness in life. What they fail to realize, however, is that there need not be a direct link between drug and effect if the drug use provides anticipation. The mere knowledge that there is "a port in the storm" of internal mental life (whether it be provided through cocaine 23 , opium , MDMA , marijuana, or prayer) can provide one with happiness indirectly. Again, this is a psychological truism that reductionists seem always to ignore, constantly asking: "Yes, but how exactly does drug x, y or z decrease depression? What are the chemicals involved?"
The answer is, of course, that the drugs do not, strictly speaking, decrease depression at all: rather, they provide the user with anticipation of upcoming mental relief through use of said substances - and that mere anticipation does all the heavy lifting: anticipation does all the positive psychological work that the reductionist wants to ascribe scientifically to the drug itself.
And so the approval of MDMA as a drug to treat depression becomes unnecessarily problematic, as reductionist science scrambles to show chemical pathways whereby the MDMA can bring about the increased happiness with which it's associated, completely ignoring the powerful role that anticipation of regular MDMA therapy can play in boosting mood and one's own patience with the downsides of daily experience. (At least I fear that this could happen. I have no specific knowledge of the actual state of affairs viz. such research.)
I'm not saying that MDMA cannot have a direct and positive effect on the brain. I'm saying that this is not the only way that we can justify the use of such a substance in a psychotherapeutic setting. We need not downplay and ignore the simple fact that occasional scheduled MDMA use can improve a user's life through mere anticipation of the psychological relief and insights that the drug can supply in a positive setting.
Speaking personally, I would definitely look forward to such a psychiatric appointment and be happier simply in knowing that this appointment loomed on the horizon. What a contrast to the depression I currently feel knowing that a pro forma office visit is coming up: a visit that I'm forced to make every 3 to 6 months of my life in order to obtain re-authorization for my purchase of yet another expensive set of prescription drugs. (That's the problem with the DEA: they fetishize drugs, making them so "awesome" that even a user of 40 years cannot be trusted to use his medicine wisely without constant bureaucratic oversight, approval and reapproval.)
PPS I hope you don't mind, but this email will also appear on my website, where I hope my thoughts on this topic will inspire thinkers to unravel the tangled web of superstition and pseudoscience that currently constitutes America's anti-scientific attitude toward this fetishized scapegoat for social problems that we call "drugs." I trust that it "goes without saying" that these are simply general philosophical observations, not criticisms directed toward you personally. So thank you for your patience and attention, and I wish you best of luck in your important work with MDMA 4 as a psychotherapeutic tool.
The Links Police
Do you know why I stopped you? That's right, because the Drug War has given me carte blanche to be a noxious busybody. That, and I wanted to give you a few more links showing how drugs can help us stop mass shootings, as soon as we drop the drug-war ideology of substance demonization, that is.
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March 1, 2023
Michael has not yet quite seen his way clear to get back to me, but then this was written three years ago when I was still a kid -- scarcely 62 years old if I was a day! What I was trying to say above is that the use of drugs like coca and opium 5 can create a virtuous circle of effects -- by giving someone something to look forward, taking one's mind off of negative thoughts, thereby improving performance, thereby making one happy, thereby taking one's mind off negative thoughts, thereby improving performance, etc.
That's a virtuous circle to which modern scientistic psychology is blind! And so they do not want to give drugs that will merely help: no, they want to "cure" me with drugs that work based on what one can see under a microscope. The result of such scientism, of course, is today's psychiatric pill mill 6 , thanks to which 1 in 4 American women are hooked on Big Pharma 78 meds that purport (wrongly, as it turns out) to treat depression and anxiety on a "scientific" basis. I'm something of an expert on this topic, as I have been on the receiving end of such nostrums for 40+ years, and the one thing I can say about tricyclics, benzodiazepines, SSRIs and SNRIs is that they are and have been all about TRANQUILIZING ME, not about making me happy or giving me a feeling of success or giving me something to look forward to in this life.
This is why the foes of suicide are doing absolutely nothing to get laughing gas into the hands of those who could benefit from it. Laughing is subjective after all. In the western tradition, we need a "REAL" cure to depression.
All drugs have potential positive uses for somebody, at some dose, in some circumstance, alone or in combination. To decide in advance that a drug is completely useless is an offense to reason and to human liberty.
Google founders used to enthuse about the power of free speech, but Google is actively shutting down videos that tell us how to grow mushrooms -- MUSHROOMS, for God's sake. End the drug war and this hateful censorship of a free people.
Imagine educational documentaries showing how folks manage to safely incorporate today's hated substances into their life and lifestyle.
LA Police Chief Daryl Gates said drug users should be summarily executed. William Bennett said drug dealers should be beheaded. These are the Nazi attitudes that the drug war inculcates. This racist and brutal ideology must be wiped out.
Did the Vedic People have a substance disorder because they wanted to drink enough soma to see religious realities?
The press is having a field day with the Matthew Perry story. They love to have a nice occasion to demonize drugs. I wonder how many decades must pass before they realize that people are killed by ignorance and a corrupted drug supply, not by the drugs themselves.
We might as well fight for justice for Christopher Reeves: he was killed because someone was peddling that junk that we call horses. The question is: who sold Christopher that horse?! Who encouraged him to ride it?!
The UN of today is in an odd position regarding drugs: they want to praise indigenous societies while yet outlawing the drugs that helped create them.
I should have added to that last post: "I in no way want to glorify or condone drug demonization."